One product, one panel, one record.
Culturelle Pro Strength Probiotics (12B CFU, 60 ct) — label audit
"Pro Strength" contains 20% less of the same strain than the brand's own plainly-named Health & Wellness capsule sold on the same site — and the brand's own footnote reveals the benchmark it is actually using: "Versus 10 Billion CFUs in Culturelle® Digestive Daily Probiotic capsules."
This page is an audit of a label. It records what this product’s panel discloses, what of that could be checked against a primary record, and what could not. The score below ranks this product on that disclosure and on nothing else.
The record this page rests on
- NIH label record
- Label read on
- The most recent dated artefact behind this page. Labels change; this is how old our reading of it is.
- Cohort
- Addendum — outside the founding denominators Torn down 2026-07-31, after the founding cohort of 27 was frozen. It sits outside every D27 denominator the site publishes.
- How deep this went
- Full forensic teardown Panel transcribed, every strain designator queried, every certification chased to its issuer’s own register, and the literature behind each marketing claim opened and read.
- What did not survive verification
- Part of this page was refuted or could not be reproduced The "Synbiotic" question is not closed, and nothing quantitative about the 200 mg of inulin may be published from this record. The teardown ran inulin[tiab] AND "200 mg"[tiab], which returns 58 records, and did not read them; it therefore makes no claim that 200 mg is a sub-threshold prebiotic dose and no claim that no trial exists at that amount, and a dose multiple that has not been sourced must not be shipped. What is publishable is only that the label states 200 mg, attaches no dose-effect claim to the inulin, and cites no inulin study. Separately, this SKU has no verified price on any surface the manufacturer controls, so it has no cost per day, and its entire panel comes from the federal label record because the retail listing serves no Supplement Facts at all.
The Label Verifiability Score for this product
100.0 out of 100
Rank 1 of the 154 products in this audit the rubric can score. This rank is shared with 18 other products — 19 products sit on 100.0 and are tied. They hold the position jointly; no tiebreaker is applied, because every tiebreaker available here would be a number the rubric deliberately refused to weigh, smuggled back in to make a list look tidier.
The score measures one thing: how much of what you are buying this company tells you, and how much of that survives being checked against a source that is not the company. It does not measure whether the product works — this site holds no efficacy data of its own, and 0 of 294 organism slots in the founding cohort carry a strain with a human randomised trial for any male-specific outcome, so nobody in this category has evidence that would support a ranking by effect.
Computed over 86% of the rubric by weight — the share of the five questions below this record could answer. The remaining question is unanswered, and unanswered is not nought: it leaves the divisor rather than dragging the score down. That share travels with the number and is never dropped — this score over 86% of the weight and the same score over all of it are different claims.
| Component | Weight | What was counted, and where | Fraction | Weight × fraction |
|---|---|---|---|---|
| Strain identity printed on the panel | 0.24 | 1 of 1 organism slot carries a printed strain designator. | 1 / 1 = 1.0000 | 0.2400 |
| Per-organism amount printed | 0.20 | 1 of 1 organism slot has an amount of its own; the rest are inside a blend total. | 1 / 1 = 1.0000 | 0.2000 |
| What the CFU count is measured against | 0.22 | Potency basis "through-expiry": CFU figure printed yes, single basis stated yes, basis reaches expiry yes — 3 of 3. | 3 / 3 = 1.0000 | 0.2200 |
| Printed designators that lead to a human trial | 0.20 | 1 of 1 checked organism slot resolves to at least one human randomised trial under the designator exactly as printed. This counts whether the identity leads to a trial, never what the trial found. | 1 / 1 = 1.0000 | 0.2000 |
| Certification confirmed at the issuer’s own register | 0.14 | Every certification on this record is brand-asserted with the register unreachable, or not yet queried. An unreachable register is a fact about the verification infrastructure, not about this brand, so it may not move its position. | Not answered | — excluded from the divisor, not counted as nought |
0.8600 — the last column added up — divided by 0.86, the weight this record could answer, is 1.0000. Multiplied by 100 and rounded to one decimal, that is the 100.0 above.
See this product’s row in the full ranking, alongside the other 153 scored products, or read what each of the five components asks and how to check it .
What this label discloses
Everything in this table is what the product itself states — on the printed panel, on the brand’s own page, or in the label record the manufacturer filed. Nothing in it is checked yet; checking is the next section.
| Disclosure | As recorded |
|---|---|
| CFU as printed | 12 billion |
| What that count is measured against | Through expiry |
| Strain designators | All organisms coded |
| Organism slots transcribed here | 1 — the full panel |
| Marketed as | Unisex |
"Guaranteed potency through date on box when stored as directed."
The panel’s own words on potency, verbatim.
The panel guarantees the count through the expiration or best-by date. This is the only basis that is falsifiable by a reader holding the bottle.
Every organism on the panel carries a printed strain designator. Whether those designators lead anywhere is a separate question, answered below.
| Organism as printed | Designator as printed | Quantity as printed | What the designator resolves to | The query we ran |
|---|---|---|---|---|
| Lactobacillus rhamnosus (correct name: Lacticaseibacillus rhamnosus) | GG | 40 mg — 12 billion | Human RCT | ("Lactobacillus rhamnosus GG"[tiab] OR "Lacticaseibacillus rhamnosus GG"[tiab] OR "ATCC 53103"[tiab]) AND randomized controlled trial[pt] → 191 |
What of that is verifiable
A disclosure is verifiable when a reader can open a record that neither we nor the brand controls and see the same thing. Below is every dated artefact this page rests on. What is absent from this list is not verified, however reasonable it sounds.
- NIH Dietary Supplement Label Database record — DSLD 273846 (opens in a new tab) captured On-market federal record, "Culturelle — Pro Strength Digestive Daily Probiotic", 60 capsules, UPC 0 49100 40143 0, entered 2022-09-22. Manufacturer of record i-Health, Inc., 55 Sebethe Dr., Cromwell CT 06416. UPC cross-check passes against the Amazon product-details table (049100401430), so every ingredient number on this page is this exact SKU. This record is the whole panel: the retail listing carries no Supplement Facts in its served HTML at all.
How many of its strains have a human trial for what it is sold for
Across the frozen founding cohort, 0 of 294 organism slots (0.0%) carry an organism with a human randomised controlled trial for any male-specific outcome. Not for this product — for all 27 of the founding teardowns, taken together. That is the number to hold against any men’s probiotic, including this one.
Two further founding-cohort figures for context: only 43 of 294 organism slots carry a strain with any human RCT at all under the exact code printed on the label, and only 2 of 27 products have a published human trial of the finished formula — the thing actually in the bottle. All three figures divide by the frozen cohort of 27 teardowns and 294 organism slots, never by every teardown on this site.
For this product specifically, 1 organism slot carries a strain with a human RCT under the exact designator printed on the label.
A word on what a designator has to clear before it counts here. The organism must be named with the exact strain code that appears in the trial, the trial must be in humans, and the code must return that trial when a reader searches it. A species name does not qualify: the trials in this field are of strains, and a species contains thousands of them.
What it costs per day
What certification it holds, checked at the issuer’s own register
A badge on a bottle is a claim like any other. Every row below was checked — or not checked — at the certifier’s own public register, never at the badge. Across the frozen founding cohort, 2 of 27 products hold a certification we could confirm at the issuer — a founding-cohort figure, not a count over every teardown on this site.
| Programme | Status at the issuer | Checked |
|---|---|---|
| "Every package of Culturelle Probiotics meets the highest standards for purity and potency when consumed" | Brand-asserted, unverified | 31 July 2026 |
"Every package of Culturelle Probiotics meets the highest standards for purity and potency when consumed"
The badge is displayed, but the register could not be reached to confirm it. We call this unverified, not false.
The entire quality claim on the retail listing. No issuer, no register, no lab, no method, no threshold. At product level the brand holds nothing: the token audit across the brand's own pages returned zero for NSF, USP, Informed Choice / Informed Sport, Non-GMO Project, any named third-party lab and the strings "third-party" and "third party", and the only named certifier in the company's trust section is FSC, which certifies paper in some of the packaging. No NSF or USP register was queried, deliberately: the brand claims neither.
How it differs from the same brand’s women’s version
Across the fourteen same-brand men’s-versus-women’s label diffs run inside the frozen founding cohort, zero men’s or default formulas contain a probiotic strain, identified by designator, that was selected on male-specific evidence. In eight of the fourteen the sex-specific differentiator is a botanical or a mineral, and in five of the fourteen the women’s SKU is better-specified, cheaper, or both — “better-specified” meaning the panel that discloses more, never the panel with more in it. The rule behind each of those counts, and all fourteen pairs classified against it , are published in full. Diffs run on teardowns added since sit outside this fourteen, and outside the sentence above.
Every finding on this page, with the record behind it
Finding 1 pro-strength-is-weaker-than-the-brands-own-health-and-wellness
Culturelle's LGG capsule ladder, all one capsule daily, all guaranteed at expiry: Digestive Daily 10 billion (DSLD 250856), Pro Strength 12 billion (DSLD 273846), Health & Wellness 15 billion (DSLD 267564). "Pro Strength" contains 20% less LGG than the plainly-named "Health & Wellness" sold on the same site. The brand's own footnote reveals the benchmark it is actually using — "§ Versus 10 Billion CFUs in Culturelle® Digestive Daily Probiotic capsules" — so "Pro Strength" means two billion CFU more than the entry SKU, while being outranked by a product with no strength word in its name at all.
The record: DSLD 273846, 267564 and 250856, all matched by UPC and read 2026-07-31 — open it (opens in a new tab)
Finding 2 synbiotic-positioning-on-200-mg-of-inulin
The Amazon title sells the word "Synbiotic" and the bullets sell "plus the prebiotic inulin*". The label amount is 200 mg. What is publishable without further work is only this: the label states 200 mg, the label attaches no dose-effect claim to the inulin and cites no inulin study, and the word "Synbiotic" is doing marketing work the panel does not substantiate on its face.
The record: DSLD 273846 ingredient table and the Amazon listing B08Y66H6B7 title and bullets, both 2026-07-31
Finding 3 no-published-price-on-any-manufacturer-controlled-surface
The SKU is not sold on culturelle.com — absent from /collections/all across 41 enumerated slugs, and the guessed slug 404s — and Amazon renders the price client-side with no price node in 2.7 MB of served HTML. A line extension priced only where the manufacturer does not control the page.
The record: culturelle.com/collections/all and amazon.com/dp/B08Y66H6B7, both fetched 2026-07-31
Finding 4 supplement-facts-absent-from-the-served-html
The string "Supplement Facts" is not found anywhere in 2.7 MB of Amazon markup for this SKU, and the brand's own pages publish their panels as images only. Every ingredient figure on this page therefore comes from the federal label record rather than from anything a shopper can see at the point of sale.
The record: amazon.com/dp/B08Y66H6B7 full-text scan and DSLD 273846, both 2026-07-31
Finding 5 the-regulatory-name-and-the-retail-name-do-not-match
The label of record is "Culturelle — Pro Strength Digestive Daily Probiotic"; Amazon sells it as "Culturelle Pro Strength Probiotics". The UPC cross-check passes — the Amazon product-details table gives 049100401430 against DSLD 273846's 0 49100 40143 0 — so the two are the same SKU under two names, which is how one product silently becomes two in review sites and price comparisons.
The record: Amazon product-details UPC 049100401430 ≡ DSLD 273846 UPC 0 49100 40143 0, matched 2026-07-31
Finding 6 proven-used-as-a-bare-verb-on-label-for-an-immune-claim
"Proven to provide digestive & immune support" and "proven effective LGG probiotic strain" appear on the label itself, not merely in ad copy. For LGG and digestive endpoints that is arguably defensible; for immune endpoints in healthy adults it leans on a thinner literature. Everything else on the listing stays inside structure/function grammar with the disclaimer correctly applied, and the antibiotic-timing instruction — "During antibiotic use, take one capsule twice daily and continue for 10 days after completion of antibiotics" — is a dosing direction rather than a treatment claim, and is the best-supported use in the LGG literature at 52 records.
The record: Amazon listing bullets and DSLD 273846 label statements, both read 2026-07-31
Finding 7 substantiation-footnote-frozen-at-january-2021
The brand's "most clinically studied" footnote is dated "as of January 2021" and is presented in the present tense in July 2026; the sibling Digestive Daily record is dated January 2019. A study count, stale, doing duty as evidence.
The record: culturelle.com footnote text and DSLD 250856, both read 2026-07-31
What we could not verify
Every gap below is published rather than deleted. Most are derived automatically from the empty fields in this page’s own record, so a gap cannot be hidden by leaving a box blank.
- "Every package of Culturelle Probiotics meets the highest standards for purity and potency when consumed" status
- The entire quality claim on the retail listing. No issuer, no register, no lab, no method, no threshold. At product level the brand holds nothing: the token audit across the brand's own pages returned zero for NSF, USP, Informed Choice / Informed Sport, Non-GMO Project, any named third-party lab and the strings "third-party" and "third party", and the only named certifier in the company's trust section is FSC, which certifies paper in some of the packaging. No NSF or USP register was queried, deliberately: the brand claims neither.
- A US retail price, and therefore the cost per day
- No price is published on any surface the manufacturer controls. Amazon returned HTTP 200 (2.7 MB) with the price rendered client-side and no price node in the served HTML, and the SKU is not sold on culturelle.com at all — it is absent from /collections/all, where 41 product slugs were enumerated, and the guessed slug 404s. That is itself the finding: a "Pro Strength" line extension priced only in channels where the manufacturer does not control the page. For context, the brand's own DTC prices per capsule are $0.5997 (Digestive Daily), $0.6997 (Health & Wellness) and $0.9163 (Women's 4-in-1).
- A men’s-versus-women’s label diff
- The same brand’s women’s SKU has not been compared against this panel.
- Any price, and therefore any cost per day
- Amazon renders the price client-side and no price node exists in the served HTML; the SKU is not sold on culturelle.com at all, being absent from /collections/all and 404ing on the guessed slug.
- The ATCC accession behind "GG", as printed
- The strain is unambiguous — GG ≡ ATCC 53103 — but the accession appears on neither the label of record nor the listing.
- Whether 200 mg of inulin is a meaningful prebiotic dose
- Deliberately left open. The teardown ran inulin[tiab] AND "200 mg"[tiab], which returns 58 records, and did NOT read them. No claim is made that 200 mg is sub-threshold and no claim is made that no trial exists at that amount. A dose multiple that has not been sourced must not be published.
- The Supplement Facts panel as served by the retailer
- The string "Supplement Facts" does not appear anywhere in 2.7 MB of Amazon markup, so the panel is absent from the served HTML entirely. Every ingredient figure on this page comes from the federal label record instead.
How to check every line of this page yourself
Nothing on this page requires trusting us. Every claim above resolves to a record you can open:
- Open the NIH Dietary Supplement Label Database record linked at the top of this page. It is the label the manufacturer filed, not our transcription of it.
- Compare the CFU line and the suggested-use line against the disclosure table above. If they disagree with us, we are wrong and we want to know.
- Take any strain designator from the panel and run the query printed beside it. The query is published precisely so you can get a different answer than we did.
- Divide the price by the number of days the label’s own dose instructions make the container last. That arithmetic is the whole of the cost-per-day row.
- Search the certifier’s own register for this product, not for the brand. A company can participate in a programme without this product being on its list.
Two words on the front of this box are doing work the panel does not support, and the brand’s own footnote gives away which benchmark it is quietly using.
“Pro Strength” is the weaker product. Culturelle’s LGG capsule ladder, all one capsule a day, all guaranteed at expiry: Digestive Daily at 10 billion, Pro Strength at 12 billion, Health & Wellness at 15 billion. The capsule with the strength word in its name carries 20% less of the same strain than the capsule with no strength word at all, sold on the same brand’s site. And the brand’s own footnote names the comparator it is actually measuring against: ”§ Versus 10 Billion CFUs in Culturelle® Digestive Daily Probiotic capsules.” So “Pro Strength” means two billion more than the entry SKU. Both numbers come from federal label records with matching UPCs.
What is right here is real, and it is the same as its siblings. One organism, named to strain level. Potency guaranteed through the date on the box. A listing that says, explicitly and to the brand’s credit, “Daily Prebiotic Probiotic for Women & Men” — it makes no men’s claim at all, and it is in this project’s universe because retailers and listicles filed it there, not because Culturelle positioned it there.
Then the price disappears. This SKU is not sold on culturelle.com — 41 slugs were enumerated and it is not among them, and the guessed slug 404s. Amazon renders the price client-side, so there is no price node in 2.7 MB of served HTML. A “Pro Strength” line extension exists only in channels the manufacturer does not control, and no cost per day can be computed for it. The same 2.7 MB contains no “Supplement Facts” string either: every ingredient figure on this page comes from the federal record, because there is nothing else to read.
One thing this page deliberately does not say. The listing sells the word “Synbiotic” on 200 mg of inulin. The label states the amount, attaches no dose-effect claim to it, and cites no inulin study — that much is publishable. Whether 200 mg is a meaningful prebiotic dose was not established, and no multiple or adequacy verdict may be quoted from this record until it is.